Critics of the organization of industrial work under capitalism have ranged from the “human relations” school to socio‐technical systems theorists and, most vociferously, to advocates of labor process theory (LPT). Their practical influence on management was small as long as production was rolling on and profits rolling in. When competition intensified, however, employers started to question old ideas and, abetted by the needs of new computerized technology, began to broaden jobs, allow workers greater discretion in their performance and involve them (...) in shop floor decision making. LPT, however, has not contributed to this evolution toward more satisfying work. This paper explains why this is so by exploring two major shortcomings of LPT. First and foremost is that LPT has ignored the efficiency of the work process, refusing to acknowledge the legitimacy of a tradeoff between work “goodness” and productivity.As a result, LPT has been unable to propose economically viable alternatives to existing job design and work organization. Second, LPT has identified management's goal in organizing work as gaining control of the process, when, in fact, it has been to make the process as economically efficient as possible. Thus, LPT could not see that, under changed circumstances, management might decentralize control toward the shop floor, if that might promote efficiency. LPT's founder, Harry Braverman, and his disciples believed that it was impossible to reform work under capitalism, but experience shows otherwise. (shrink)

If all the fundamental constants x of physics were expressed in one set of units (e.g., mks) and then used as pure numbers in one overall histogram, what shape would that histogram have? Based on some invariances that the law should reasonably obey, we show that it should have either an x−1 or an x−2 dependence. Empirical evidence consisting of the presently known constants is consistent with an x−1 law. This is independent of the system of units chosen for the (...) constants. The existence of the law suggests that the fundamental constants may have been independently and randomly chosen, at creation, from it, and hence that at the next “big bang” randomly a different set will be produced. Also, because of the law, the number 1.0 has an interesting cosmological property: it is the theoretical median of all the fundamental constants. Finally, as a practical matter, the law predicts that current methods of evaluating the fundamental constants are biased toward overly large numbers. A correction term is given for each of three kinds of noise. (shrink)

Though dividing one’s attention between two input streams typically impairs performance, detecting a behaviorally relevant stimulus can sometimes enhance the encoding of unrelated information presented at the same time. Previous research has shown that selection of this kind boosts visual cortical activity and memory for concurrent items. An important unanswered question is whether such effects are reflected in processing quality and functional connectivity in visual regions and in the hippocampus. In this fMRI study, participants were asked to memorize a stream (...) of naturalistic images and press a button only when they heard a predefined target tone. Images could be presented with a target tone, with a distractor tone, or without a tone. Auditory target detection increased activity throughout the ventral visual cortex but lowered it in the hippocampus. Enhancements in functional connectivity between the ventral visual cortex and the hippocampus were also observed following auditory targets. Multi-voxel pattern classification of image category was more accurate on target tone trials than on distractor and no tone trials in the fusiform gyrus and parahippocampal gyrus. This effect was stronger in visual cortical clusters whose activity was more correlated with the hippocampus on target tone than on distractor tone trials. In agreement with accounts suggesting that subcortical noradrenergic influences play a role in the attentional boost effect, auditory target detection also caused an increase in locus coeruleus activity and phasic pupil responses. These findings outline a network of cortical and subcortical regions that are involved in the selection and processing of information presented at behaviorally relevant moments. (shrink)

A new information matrix [F] with elements F mn = 〈 (y m - a m )(y n - a n) (∂ ln p(y | a)/∂a m ) (∂ ln p(y | a)/∂a n ) 〉 is analyzed. The PDF p(y | a) is the usual likelihood law. [F] differs from the Fisher information matrix by the presence of the first two factors in the given expectation. These factors make F mn unitless, in contrast with the Fisher information. This lack (...) of units allows F mn values from entirely different phenomena to be compared as, for example, Shannon information values can be compared. Each element F mn defines an error inequality analogous to the Cramer-Rao inequality. In the scalar case F mn ≡ F, for a normal p(y|a) law F = 3, while for an exponential law F = 9. A variational principle F = min (called FMIN) allows an unknown PDF p(x) to be estimated in the presence of weak information. Under certain conditions F obeys a “Boltzmann F-theorem” ∂F/∂t ⩽ 0, indicating that F is a physical entropy. Finally, the trace ℱ of [F] may be used as the scalar information quantity in an information-based principle for deriving distribution laws p of physics. (shrink)

We show that the minimum Fisher information (MFI) approach to estimating the probability law p(x) on particle position x, over the class of all two-component laws p(x), yields the complex Schrödinger wave equation. Complexity, in particular, traces from an “efficiency scenario” (demanded by MFI) where the two components of p(x) are so separated that their informations add.

An empirical investigation was conducted to determine whether management information systems (MIS) majors, on average, exhibit ethical decision-making processes that differ from students in other functional business areas. The research also examined whether the existence of a computer-based information system in an ethical dilemma influences ethical desision-making processes. Although student subjects were used, the research instrument has been highly correlated with educational levels attained by adult subjects in similar studies. Thus, we feel that our results have a high likelihood of (...) generalization to the MIS professional community. The results indicate that MIS majors exhibit more socially-oriented ethical decision-making processes than non-MIS majors measured by the Defining Issues Test. The results also indicate that the existence of a computer-based information system in an ethical dilemma may influence ethical decision-making processes. The study makes no statement regarding MIS majors making more (or less) ethical decisions. The business ethics literature is reviewed, details of the study are presented, implications for management are considered, and directions for future research are suggested. (shrink)

Recent findings in several organ systems show that cytoneme‐mediated signaling transports signaling proteins along cellular extensions and targets cell‐to‐cell exchanges to synaptic contacts. This mechanism of paracrine signaling may be a general one that is used by many (or all) cell types in many (or all) organs. We briefly review these findings in this perspective. We also describe the properties of several signaling systems that have previously been interpreted to support a passive diffusion mechanism of signaling protein dispersion, but can (...) now be understood in the context of the cytoneme mechanism.Also watch the Video Abstract. (shrink)

An information-theoretic approach is shown to derive both the classical weak-field equations and the quantum phenomenon of metric fluctuation within the Planck length. A key result is that the weak-field metric $\bar h_{\mu \nu } $ is proportional to a probability amplitude φuv, on quantum fluctuations in four-position. Also derived is the correct form for the Planck quantum length, and the prediction that the cosmological constant is zero. The overall approach utilizes the concept of the Fisher information I acquired in (...) a measurement of the weak-field metric. An associated physical information K is defined as K=I−J, where J is the information that is intrinsic to the physics (stress-energy tensor Tμv) of the measurement scenario. A posited conservation of information change δI=ΔJ implies a variational principle δK=0. The solution is the weak-field equations in the metric $\bar h_{\mu \nu } $ and associated equations in the probability amplitudes φuv. The gauge condition φ v uv =0 (Lorentz condition) and conservation of energy and momentum Tv μv=0 are used. A well-known “bootstrapping” argument allows the weak-field assumption to be lifted, resulting in the usual Einstein field equations. A special solution of these is well known to be the geodesic equations of motion of a particle. Thus, the information approach derives the classical field equations and equations of motion, as well as the quantum nature of the probability amplitudes φuv. (shrink)

The posthumous retrieval and use of gametes is socially, ethically, and legally controversial. In the countries that do not prohibit the practice, posthumous assisted reproduction is usually permitted only at the request of the surviving spouse and only when the deceased left written consent. This paper presents the recommendations of an ethics committee established by the Israeli Fertility Association. In its discussions, the committee addressed the ethical considerations of posthumous use of sperm—even in the absence of written consent from the (...) deceased—at the request of either the spouse or the deceased’s parents who wish to become the offspring’s parents or grandparents. It is concluded that under certain conditions, a request by the deceased’s parents to posthumously use the deceased’s sperm is justified and should be granted. (shrink)

ICAP is a theory of active learning that differentiates students’ engagement based on their behaviors. ICAP postulates that Interactive engagement, demonstrated by co‐generative collaborative behaviors, is superior for learning to Constructive engagement, indicated by generative behaviors. Both kinds of engagement exceed the benefits of Active or Passive engagement, marked by manipulative and attentive behaviors, respectively. This paper discusses a 5‐year project that attempted to translate ICAP into a theory of instruction using five successive measures: (a) teachers’ understanding of ICAP after (...) completing an online module, (b) their success at designing lesson plans using different ICAP modes, (c) fidelity of teachers’ classroom implementation, (d) modes of students’ enacted behaviors, and (e) students’ learning outcomes. Although teachers had minimal success in designing Constructive and Interactive activities, students nevertheless learned significantly more in the context of Constructive than Active activities. We discuss reasons for teachers’ overall difficulty in designing and eliciting Interactive engagement. (shrink)

If A then B: How the World Discovered Logic is a historically oriented introduction to the basic notions of logic. In particular, and in the words of the authors, it is focused on the idea that ‘lo...

Background: Although convolutional neural networks (CNNs) achieve high diagnostic accuracy for detecting Alzheimer’s disease (AD) dementia based on magnetic resonance imaging (MRI) scans, they are not yet applied in clinical routine. One important reason for this is a lack of model comprehensibility. Recently developed visualization methods for deriving CNN relevance maps may help to fill this gap as they allow the visualization of key input image features that drive the decision of the model. We investigated whether models with higher accuracy (...) also rely more on discriminative brain regions predefined by prior knowledge. Methods: We trained a CNN for the detection of AD in N = 663 T1-weighted MRI scans of patients with dementia and amnestic mild cognitive impairment (MCI) and verified the accuracy of the models via cross-validation and in three independent samples including in total N = 1655 cases. We evaluated the association of relevance scores and hippocampus volume to validate the clinical utility of this approach. To improve model comprehensibility, we implemented an interactive visualization of 3D CNN relevance maps, thereby allowing intuitive model inspection. Results: Across the three independent datasets, group separation showed high accuracy for AD dementia versus controls (AUC ≥ 0.91) and moderate accuracy for amnestic MCI versus controls (AUC ≈ 0.74). Relevance maps indicated that hippocampal atrophy was considered the most informative factor for AD detection, with additional contributions from atrophy in other cortical and subcortical regions. Relevance scores within the hippocampus were highly correlated with hippocampal volumes (Pearson’s r ≈ −0.86, p < 0.001). Conclusion: The relevance maps highlighted atrophy in regions that we had hypothesized a priori. This strengthens the comprehensibility of the CNN models, which were trained in a purely data-driven manner based on the scans and diagnosis labels. The high hippocampus relevance scores as well as the high performance achieved in independent samples support the validity of the CNN models in the detection of AD-related MRI abnormalities. The presented data-driven and hypothesis-free CNN modeling approach might provide a useful tool to automatically derive discriminative features for complex diagnostic tasks where clear clinical criteria are still missing, for instance for the differential diagnosis between various types of dementia. (shrink)

There are few philosophical questions to which Charles Taylor has not devoted his attention. His work has made powerful contributions to our understanding of action, language, and mind. He has had a lasting impact on our understanding of the way in which the social sciences should be practised, taking an interpretive stance in opposition to dominant positivist methodologies. Taylor's powerful critiques of atomist versions of liberalism have redefined the agenda of political philosophers. He has produced prodigious intellectual histories aiming to (...) excavate the origins of the way in which we have construed the modern self, and of the complex intellectual and spiritual trajectories that have culminated in modern secularism. Despite the apparent diversity of Taylor's work, it is driven by a unified vision. Throughout his writings, Taylor opposes reductive conceptions of the human and of human societies that empiricist and positivist thinkers from David Hume to B.F. Skinner believed would lend rigour to the human sciences. In their place, Taylor has articulated a vision of humans as interpretive beings who can be understood neither individually nor collectively without reference to the fundamental goods and values through which they make sense of their lives. The contributors to this volume, all distinguished philosophers and social theorists in their own right, offer critical assessments of Taylor's writings. Taken together, they provide the reader with an unrivalled perspective on the full extent of Charles Taylor's contribution to modern philosophy. (shrink)

We begin with a prepositional languageLpcontaining conjunction (Λ), a class of sentence names {Sα}αϵA, and a falsity predicateF. We (only) allow unrestricted infinite conjunctions, i.e., given any non-empty class of sentence names {Sβ}βϵB,is a well-formed formula (we will useWFFto denote the set of well-formed formulae).The language, as it stands, is unproblematic. Whether various paradoxes are produced depends on which names are assigned to which sentences. What is needed is a denotation function:For example, theLPsentence “F(S1)” (i.e.,Λ{F(S1)}), combined with a denotation functionδsuch (...) thatδ(S1)“F(S1)”, provides the (or, in this context, a)Liar Paradox.To give a more interesting example,Yablo's Paradox[4] can be reconstructed within this framework.Yablo's Paradoxconsists of an ω-sequence of sentences {Sk}kϵωwhere, for eachnϵω:WithinLPan equivalent construction can be obtained using infinite conjunction in place of universal quantification - the sentence names are {Si}iϵωand the denotation function is given by:We can express this in more familiar terms as:etc. (shrink)